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a case of the red ass 

classic phrase to be heard from the very very old people in the south, generally.

to mean pissed off. angry.
yo mawma sho got hahsayelf a cayas of da rayed ayss t'day.

your momma sure got herself a case of the red ass today.

a case of the red ass 

pain and redness of the ass after a day of the shits
If i don't stop shitting. I'm going to have a case of the red ass.