Wuye Share definition Flag Another definition for Marijuana. Every time we got to that guy he give us the best wuye in town. It stinks and is super sticky. Smells like a mix of a skunk and baby diarrhea. Yum. Wuye by coffeeoso August 28, 2007 0 0 Get merch Get the Wuye mug. Buy Now — $32.95 See more merch