The act of waking up and starting your day by ingesting large amounts of speed, preferably by method of insufflation.
Jimmy started his day with a wake and shake- he woke up and immediately started blowing his brother's prescription of adderall. Five minutes later he started to clean his entire house.
The young woman, Britt, demanded that Dale be on MSN when she awoke so she could Wake and Shake, although she knew she secretly wanted to ask Ava to assist in her Nap and Slap.