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The opposite of "unputdownable". Refers to a book, usually highly regarded by others, that you can read only a small portion of, before putting it down: never to be touched again.

Ref:
http://www.multiverse.org/fora/showthread.php?t=8385
"How did you like Pyncheon's 'Gravity's Rainbow'"?
"Totally unpickupagainable"
by UncleDes July 19, 2008
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