To smoke so much crystal meth that one becomes "woke". The brand of woke achieved by twoke individuals is marked by an unreasonable obsession with shoddily-constructed conspiracy theories and the constant use of the word "sheeple". Twoke is a portmanteau of the words "tweak" and "woke".
Person A: Did you see Dave's Facebook rant where he said reptiliansinvented COVID and he called me a sheeple?
Person B: Yeah, man. That guy's been holed up in his room getting twoke for like two weeks now.
The state of freaking out, overreacting, or losing your mind in a dramatic and often irrational way. Can be caused by stress, an ex showing up unannounced, sending a risky text, or just general life chaos.
"I twoke when I saw my ex walk into the party."
"She twoke after realizing she sent a text to the wrong person."
"Bro, I twoke so bad during that exam, I forgot how to read."
"He twoke when she left him on delivered for six hours."