The gastrointestinal consequence upon the consumption of nicotine after having just woken up from a long nap or night of sleep. Symptoms of The Nic Shits include stomach cramps, bowel movements, and on the rare occasion, diarrhea.
Person 1: Sorry I'm late bro, I got the nic shits this morning after I hit my juul in the shower.
Person 2: All good man, we've been there.
by chuckschrodinger March 13, 2019
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The explosive mondo dukes that result from...
a. Too much nicotine

b. Pod that does not suit the respiratory system (e-cigarettes)
c. Being incapable to handle nicotine in the body, and thus exits through an explosion out of one’s anus
Damn... I just went through a whole pod and had the worst nic shits of my life! Bitch sorry about your toilet it was like a grenade blast in that shit. I’ll pay half for a new can.
by Cranjus McBasketball IV March 17, 2018
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After a long period of time after hitting a vape or Juul that has high nicotine percentage, you have the urge to poop caused by the nicotine calling it a nic shit
“Yo Brady I just had the biggest nic shit ever my stomach hurts so bad

#DI4J
by JuulSZNN127 May 15, 2018
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When you always fiend in the bathroom so when you want a hit you have the sudden urge to take a dump
“I gotta hit the bathroom
“again?”
“yeah i’ve got the nic shits.”
by Ppnecker87 February 3, 2020
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