Defined as the female's climax in response to sexual stimulation.
My sweet babboo gives me The Big O and I am his slave for a week.
by THE REAL JULIA December 27, 2005
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There has never been a basketball player more versatile than The Big O.
by IcebergSlim78 March 13, 2009
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Paradigm City is a place without a past. 40 years ago, something happened that wiped away the memories of everyone in it. Unfortunately, the people of Paradigm City were very busy before then, making Megadueses (giant robots) and monsters. People who were born after the memory wipe are gaining/recovering memories of the past and using them to build newer threats. Roger Smith keeps Paradigm City safe with the help of The Big O (a faithful giant robot), his butler Norman, and the android Dorothy. As problems mount and more memories surface, Roger's past and Paradigm's future begin to become suspect.
Big O aired in the U.S. on Toonami in 2001. There are a total of 26 episodes.
by ♫ Highway to Hell ♫ September 11, 2010
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super intense orgasm in which female ejaculate is released (not urine)... speculation puts phenomena at 1 out of 20 women able to achieve
by TXDOC March 29, 2006
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1. an orgasm, a sexual climax

2. opium
Once I reach the big O, there is no turning back.
by The Return Of Light Joker November 5, 2007
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"The Big O" with a woman has been elusive for Pete for many years.
by Total Penetration June 4, 2005
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