When a friend is telling a story that is supposed to be funny and entertaining but isn't quite that, you say "Now, twist it funny." to declare to your friend that you will not carry on with the conversation, untill a punchline has been dropped.
That guy: "As i was trekking through Nicaragua, heading towards a a childrens orphanage where I would deliver supplies, I met so many interesting cultures that really helped shape me as a person, I feel like i have changed in a profound way."
You yawn because you have heard this story too many times and responds. "Okay. Now, twist it funny." and sit back and enjoy the akward moment that ensues.
One level higher than the common term, "don't get it twisted."
When a guy/girl already got it twisted and you're warning them not to twist it up anymore.
It means getting to the point where you won't be able to undo what's done.
Him: Where you taking me tonight baby? Do you think this dick is free?
Her: I'm the prize, baby. Don't twist it up.
Pajama casual is a term used when working from home and preparing for a video conference. All business above the waist and your pajama pants down below.