The fucking article. Often used in the construct RTFA (read the fucking article), itself derived from RTFM, it is often used on the slashdot news site, where it is common knowledge that most of the posters will comment on stories without reading the articles linked to in the main story.
TFA clearly states that your point is utter BS. So, next time, please RTFA before making a fool out of yourself on /.
by Anonymous Coward April 8, 2005
During the early reign of President Donald Trump, TFA (and #TFA) was popularized by certain White House staff to describe the potential outcome to President Trump's crazy rants an weird behaviour. TFA is short for 25th Amendment to the US Constitution, wherein a process is outlined for removing a sitting president if they cannot perform their duties (e.g. due to a grave illness), or, in this case, if he is just acting batshit insane all the time. Word.
"Hey Omarosa! Did you hear that shit DJT said about Charlottesville and how both sides were bad and that Nazis were good people?!?" "Gurrll, you know how I feel about that. #TFA"
by DynoFarkJr September 10, 2018
Two Factor Authentication. Or Three Factor Authentication. (You see, there's ambiguity in the definition of this TLA)

In most situation, you only need a single factor to authenticate, to prove who you are: "Something you know" - typically a password. But that's not very secure. Therefore, some systems make authentication stronger by requiring more than just one factor. Other factors are "something you are" (such as your fingerprint, or other biometric aspects such as your signature) and "something you have" (such as a key, or a chipcard).
Every ATM I have seen so far employs TFA: In order to get money out of it, you have to prove that you're the legitimate account holder by providing two things: Something you have (your ATM card) and something you know (your PIN).
by Securitoot January 15, 2013
1. Total Fucking Annihilation - An irrefutable display of grisly power that completely, mercilessly, and swiftly obliterates an object or entity without significant opposition.

2. Totally Fucking Annihilate - To completely, mercilessly, and swiftly obliterate an object or entity without significant opposition.
i. If that little kid hadn't moved out of that eighteen-wheeler's way, we would have witness a prime example of TFA.

ii. You mean they dropped a nuke on a fetus? Why the hell did they TFA a fucking fetus?!?
by Dafydd January 8, 2006
Twenty-Fifth Amendment
Thanks Omarosa. You granted legitimacy to a racist president and now - #TFA is a thing.
by anyrandomname September 11, 2018