Sweaty Sack Syndrome (a.k.a. S. S. S) Share definition Flag When one genital sack is becomes sweaty and adjutated. this can result in a rash. GUY:God Damn S. S. S. GIRL:Ewww Sweaty Sack Syndrome (a.k.a. S. S. S) by Stiffanie June 10, 2005 0 0 Get merch Get the Sweaty Sack Syndrome (a.k.a. S. S. S) mug. Buy Now — $32.95 See more merch