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Strikeout 

A Strikeout is possibly one of the most brilliant and best ways to get totally inebriated. The person in question must have ready a fully loaded Bong, a shot of his or her favourite liquor, and a pint of his or her favourite Beer.

The person in question then lights the bowl, takes a nice, long bong hit, then puts the bong down. While holding the weed smoke in, the person proceeds to take the shot of liquor back and then chugs the beer back. After they finish the beer, they exhale the weed smoke.
Guy #1: Man, what a sick party last night eh?
Guy #2: Yeah man, did you see us all doing those Strikeouts? It was so sick!
Guy #1: Dude, I was doing them with you! They must have fucked you up beyong belief
Guy #2: Hells yeah
Strikeout by Fraser August 29, 2006

ride strikers 

to drive around with shooters
we dont know if they still want smoke we gotta ride strikers
ride strikers by coltonguy March 20, 2021

strikeout 

as seen in the 2006 movie "beerfest", you take a hit (weed), chug a beer, take a shot, and blow out the smoke
a strikeout will FUCK you up...
strikeout by sexy ukrainian August 27, 2006

Down Syndrome Strikeout

when two homosexual boys with down syndrome sit on a couch by a warm cozy fire and take turns giving each other oral sex then all of a sudden one of them unexpectedly shoves the other boys entire ball sack in his mouth and gnaws the stretched skin off and swallows it whole then rips off his own testicles and wedges them inside of his asshole then takes his hand and slaps himself across the face then yells at the other boy in laughter and excitement"STRIKE THREE I'M OUT" then jumps into the fireplace. The other boy crys in agony because he knows he was defeated by a true champion.
Sebastian- I wonder what people with Down Syndrome do with there free time.

Derrik- They play Down Syndrome Strikeout

Sebastian- Whats that like retard baseball?

Derrik- Lets just say the two are quite similar.

the strikeout 

Taking a hit from a bong, drink a shot and then chug a beer all before blowing out the smoke.
Did you see when that guy did the strikeout at the party last night?
the strikeout by MWR September 23, 2008

Verbal Strikeout

When somebody tries to either:

a. Tell a story
b. Say a sentence
c. Get a point across

but has to restart at least 3 times, you can call for a quick end to their speech by shouting "VERBAL STRIKEOUT". Three strikes you're out. The conversation must then make a complete shift and move on to another topic.
Guy 1: Hey man, last night was crazy, I was at a frat house and- well I was at my FRIENDS frat house then- but wait hold up- It might have been two days ago-

Guy 2: *rudely interrupts* YOU'RE OUT! Shut up now.

Guy 1: Wtf bro?

Guy 2: Verbal strikeout, duh.
Verbal Strikeout by 1337 Fork April 20, 2009