O.D. 

overdose; generally fatal, in so much as that one's system cannot handle the quantity of drug being pumped into it; hence death; generally a body-wide systems failure.

as drugs become the more popular venue of entertainment/escape the rate of O.D. rises in accordance.

O.D. by Ilianivich March 15, 2003

O.D. 

To over-do; An unnecessary overexageration.

You swam through the Atlantic? That's O.D. Stop lying...

O.D. by Daphya .aka. Melizzah A. December 26, 2004

O.D. 

over-doing something

he O.D.ed with that fight

O.D. by toudai_ronin April 13, 2003

O.D. 

over dose

I o.d.ed on crack.

O.D. by The Dickey March 15, 2003

O.D. 

over dosed, over did something

Oh my god dat car accident was O.D., I said you could have a sip but you just O.D.'d on my soda.

O.D. by >[BoBbY d]< April 20, 2008

O.D. 

O.D. can stand of overdose/over doing/too much of something or also oh dayum!

john- See that girl over there? yeah i tapped her.
matt- O.D.!!!!!!!!

matt- shit i dropped my phone again
john- O.D.!!

O.D. by o.d. that niggas dirty November 30, 2009

O.D. 

Someone who is going overboard with the situation.

(Standing in line while getting their lunch.)
Person A: I don't even know why I go nachos, I didn't really want it.
Person B: So throw it away.
(Principal Ms. Lee walks by and Person A dumps their lunch on her)
Person A: That's O.D., son!

O.D. by DJ SKILLZ May 29, 2007