O&D 

Origin and Destination

"She is my O&D!"

O&D by hahaha7140 May 22, 2016

O&D 

Abbreviated version of One & Done which means you're only doing a one night stand with someone you'll ghost right afterwards

Friend: Hey, whatever happen to Gary?
Me: I O & D him cause the dick was trash
Friend: You did what?
Me: I One & Done him aka O&D

O&D by igot__issues March 4, 2021

O.D 

Over Dose. Mostly used in the slang way as in, it went past the limit:

That was O.D when the police killed the innocent lady.

O.D by Jomairy January 15, 2003

O D 

O D means to overdose on something, to take an excessive amount of something.

Alyssa O D'd on dick so now she's mudded out.

O D by Miss Thickness December 30, 2005

O.D. 

overdose; generally fatal, in so much as that one's system cannot handle the quantity of drug being pumped into it; hence death; generally a body-wide systems failure.

as drugs become the more popular venue of entertainment/escape the rate of O.D. rises in accordance.

O.D. by Ilianivich March 15, 2003

o.d 

Over Doing it

the way jesus got beat was o.d

o.d by Eric April 3, 2004

O.D. 

To over-do; An unnecessary overexageration.

You swam through the Atlantic? That's O.D. Stop lying...

O.D. by Daphya .aka. Melizzah A. December 26, 2004