The polite way to describe somthing that is "fucked up"
Jack muffed up Jason's face after Jason attempted to finger Jacks mothers asshole while she was sleeping.
by scott January 30, 2004
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muffed up means fucked up. use "muff" to replace fuck. very fun to use so you dont get in trouble by the parentals or offend the old folks. use different variations of muff too-muffer, muffing, etc.
That's muffed up dude!
Go muff yourself.
by Kyle Ernesti June 17, 2006
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synonym for fucked up.

slang term that is often used on Call of Duty Modern Warfare 2
Alex: Dude what did Sam do?

Tyler: He cried after getting high

Alex: Thats muffed up
by Alex Hildenbrand May 6, 2010
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phrase referring to fucking up sex by not shaving your muff
We was about to hit it right, but i reached in, felt that bush and though "damn, this bitch muffed up." She knew she muffed up too.
by Fisherella June 30, 2009
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"Fucked-up hoe-bag" as censored by FXM when they air 'The Descendants'
Alexandra King: "Hey, Scottie! Raina's a muffed-up low-bag and you need to stay away from her! And she's going to be a meth-head and she's gonna get used by stupid guys!"
by Deviant and Shaven March 7, 2014
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