Mr. Glad-Hand Share definition Flag Somone like a politician who goes goes up and shakes everyone's hand with a great big smile. Feighned "Glad to meet ya." Look at that jerk-off Mr. Glad-Hand cheeze-balling the crowd. Mr. Glad-Hand by ellmanholmes July 10, 2011 0 0 Get merch Get the Mr. Glad-Hand mug. Buy Now — $32.95 See more merch