Mcnonips Share definition Flag A person who becomes so frazzled/ stressed/ baffled/ overworked that they "lose their nipples". One could avoid this by simply relaxing or "calming their nips". Dave: Look at Mcnonips over there.Andrew: Ya, someone needs to chill. Mcnonips by Hank Mardukis69 November 6, 2011 Get the Mcnonips mug.