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Mc is derived from the American fast food place McDonald's. Whore is derived from old english. Mc specifies that it is a food. A whore is a woman/man who engages in sexual acts for money. So a mcwhore is a whore on a bun with toppings served to you easily.
I'd like to order two Mcwhores please.

Davin your such a wanna be Mcwhore!
Mcwhore by Muscle Man April 23, 2009
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A McDonald's employee who is a slut
Typical to take nudes in their uniform or fuck coworkers
"Yo bro you see that mcwhore?"

"Yeah."

"She sucked my dick in the freezer bro."

"What a mcwhore."
McWhore by slut_fire November 1, 2015
a fat (supersized) girl who will do pretty much anything for $3.99.
Check out that McWhore. Not too easy on the eyes but she's easy on the bone.
McWhore by badazz March 3, 2004
Seriously? Do you have anything better to do than screw everyone else's man, or are you just a McWhore?
McWhore by alfeef September 8, 2010

Slutty McWhore 

A giant fucking whore who is always a whore and a fucking slut too!!
There goes Slutty McWhore off to suck a handfull of cocks
Slutty McWhore by badtouch July 12, 2006

mcwhoreo 

put a bunch of oreos, in a blender, pour in milk, and then proceed to pour the shake mixture on a whores crotch then start munching
i paid a prostitute to give me head, but instead she wanted me to have a mcwhoreo
mcwhoreo by DonJuanFranko January 18, 2017

Skankface McWhorebag 

A girl of questionable morals (also known as a skeeze), who fucks anything in sight regardless of the consequences
That girl is a real Skankface McWhorebag, sleeping with all those guys
Skankface McWhorebag by CHillsCrew September 26, 2005
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I’m trying to go to this Taylor Swift concert but the funflation has made it so impossible for me to afford tickets.
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Take the big pirogue, I saw a huge swamp dog out there earlier.
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