A person, usually an ugly girl or old person, unfortunate enough to always have "bitter beer face." Usually involves lips rolled somewhat into the mouth with a cringing look across the face.
Wow that girl over there has a great body but serious loser face.
12 step recovery jargon referring to someone new who talks about how great life is, now that they're sober. Usually meaning that the person is out of touch with reality.
The new guy seems pretty happy for a dude who has no job, no money and no family. He must be on a pink cloud.