This is short for a hypochondriac, or someone who thinks they are always sick, when really it's all in their head. Hypo is an affectionate term unlike hypochondriac.
NIKKI IS A HYPO!!!!!! But we love her anyway.
by Mary & Nikki rock May 7, 2005
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The Highway patrol bitches commonly used in rural missouri, by the ticks and Nelly(the guy with the band-aid on his face)
Slow down there are hypos everywhere, Bitch!!!
by G-Murda March 1, 2003
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A cokehead. Synonyms include crackwhore, supermodel, and Kate Moss
"Have you heard anything by Babyshambles?"
"Yeah they're great. Too bad Pete Doherty is a total hypo"
by Maggie Bonadies December 11, 2005
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When Your tired as hell, but you want too stay up a little longer, you start typing like your high! because it makes people think your insane, and it may or may not help you stay Away.
Dude, she started hypoing me, and I sent her too bed.
by MadeyeIvashkova October 6, 2011
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Similar to typo an error in the hype for an event. Can be both positive and negative.
All the reviews said the Britney show was her best yet, but really it was jusy her sitting pantsless onstage. What a hypo.

When Sarah said she's bringing a special guest to the party I thought it was just her new girlfriend. I didn't realize Kanye was going to be there; what a hypo!
by parkca01 November 19, 2010
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Short for "hypochrondriac"; Someone who is unaware of their lack of popularity. (I.E., Someone who thinks they're ill.)
He is such a hypo in his Members Only jacket.
by Curtis Meyer March 25, 2008
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A self-proclaimed critic who is especially fond of criticizing anything whilst being hypocritical.
John, "Hey man what's with Greg?"
Jack, "Oh he's just a hypo-critic, just ignore him."
John, "He's always so unmannerly and today he told me I'M rude. The nerve."
by misslyss. February 24, 2011
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