If someone tells you to "Get your head out of your ass," it means that you have to start paying more attention to what's going on around you. It could also mean that you have to stop being so consumed with yourself, and your own well being, stop being so conceited.
John: I am so good at painting, I must be like Michelangelo!
Getting your thumb out of your ass means to stop wasting time doing nothing when you've got shit to do.
"Ugh, I hate English. It's so boring!"
"Yeah, well this is a Group Project, so you're not the only one one whose neck is on the line. So get your thumb out of your ass and help, you lazy fuck!"
Ruler of Lake Titicaca. Rumored to have a bunghole that gets very angry if it does not receive toilet paper. Cornholio the Great is often seen walking around with his shirt over his head and his hands in the air, chanting songs about his power, and his bunghole.
"I am Cornholio! You do not want to face the wrath of my bunghole, for I need TP!"
Butthead: Shut up, Beavis! (uh huh huh huh)
Beavis: Um, okay. (heh heh heh heh).