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Friends Zone Syndrome 

Affliction of a persons ability to form relationships with members of the opposite sex. Usually involves a person being perpetually placed in the friend zone due to his or her lack of appropriate game or ability to communicate his intentions with a female or male.
John: Hey man whats going on with Jamie?
Geoff: Man it sucks. She says im just her friend!
John: Dang man again? You got Friends Zone Syndrome Hard.
Friends Zone Syndrome by TLPeeze December 17, 2008
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friend zone syndrome 

An affliction where a patient uses "friend zone" unironically.
The patient sees friendships with people of sexual appeal as a failure.

In fact, this is actually a symptom of a number of other hidden problems (failure to meet new people regularly, failure to negotiate sexuality in an upfront way, failure to enjoy the sorts of people one is interested in sleeping with, and so on)
A: "Someone I know isn't giving me sex. I mean, I haven't been upfront, because I fear even polite rejection... But the only thing I want from them is sex, and they're the only person I am going to meet this year. Please, help me get out of the friend zone!"

B: "That's your problem: you've got friend zone syndrome."

False Friend Zone Syndrome (FFZS)

A growing epidemic that causes males to believe they have been "friend zoned" by girls they are acquainted with, yet they have never approached the girl in a manner of creating a sexual or emotional relationship. The disease stems from a lack of confidence in oneself, thus causing one to create the social construct of "friend zoning" to cope with their feeling of inferiority and lack of ability to ask a girl how she truly feels.
Infected: "Dude I totally got friend zoned the other day. It sucks so hard. Ughh forever alone."
Friend: "Sorry to hear she rejected you..."
Infected: "She didn't I just know she doesn't want me."
Friend: "Oh god...get away! What are you?!"
Epidemiologist: "Yes a perfect example of False Friend Zone Syndrome (FFZS)."

Friendzone Asshole Syndrome 

A very serious condition that can alter the mood of someone who is single and a virgin, typically causing them to ditch their friend group for a girl that does not want them. Someone diagnosed with this syndrome is typically an asshole to their friend group of guys, because there's a lot of misplaced anger.

Symptoms include, but are not limited to:

—ignoring friends
—creating awkward silences
—getting pissed over minuscule problems
—not wanting to be around anyone else, except the girl they like
—the girl they like is NOT interested in them, therefore they feel bad. See friendzone.
—this becomes a cycle where the diagnosed take out their emotions on their friend group even though the friend group is totally innocent
—clearly violating the concept of Bros before hoes

There has been no developed cure, however symptoms seem to be alleviated when the guy and the girl become distant, since the relationship becomes nothing and the guy comes to terms with it.
Stay away from Landon, boys. He's developing some serious symptoms of Friendzone Asshole Syndrome.
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