The stinging or tingling sensation created by making too many quarter-circles or half-circles on a video game controller's d-pad.
With the release of Ultimate Marvel vs. Capcom 3, I've been getting really bad fighter's thumb lately.
by AxelScar November 23, 2011
The painful condition on the inside of your thumb you get when playing too many rounds of Street fighter back to back.
by The silverback at rio May 21, 2010
the hardening of the female nipple when subjected to cold weather, resulting in her studs resembling fighter pilot thumbs
by paddy farrell September 26, 2004