Ed Zachery Disease 

Very nasty disease that prevents women from getting dates or having sex. This was coined by Dr. Kayoto, the very well-known Japanese sex therapist.

Your probrem vewy bad, you haf Ed Zachery Disease."
Ed Zachery Disease? What's that?"
"Vewy sad. It's when your face rook Ed Zachery rike your ass."

Also see Butterface, or ButHerFace

Ed Zachery Disease by TimmyH September 8, 2006

Ed Zachary Disease 

Ed Zachary Disease is when your face looks exactly like your ass, meaning you are extremely ugly.

"Ed Zachary Disease is when your face rook Ed Zachary rike your ass." - Dr. Chang of China

Ed Zachary Disease by -Brad- May 24, 2006

Ed Zachary Disease 

When someone's face looks Ed Zachary like their ass.

Once, an ugly girl that was making a pass at me described that she wasn't feeling very well.
I said, "Well, if I were a doctor, I think I might diagnose you with Ed Zachary Disease."
She asked what it was and I said, "When your face look Ed Zachary like yo ass."
She wasn't amused.

Ed Zachary Disease by Roy L'Ourtiere September 7, 2008

Ed Zachary Disease 

When a person's breath is SO BAD that their mouth smells "Ed Zachary" like their asshole.

If you do not brush your teeth you are going to have Ed Zachary Disease, and no babe will want to kiss you.

Ed Zachary Disease by makomark13 March 4, 2009