E6 

a place of no return, where one's actions add up to a punishment worse than hell

teacher: "go to E6"
student "NOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO!"

E6 by IWillStealYourRobux January 24, 2019

E6 

a shortened way of saying E621

Im going to go home and boot up E6

E6 by HarpsOwO November 13, 2018

E6 

East6 - A part of East London that often has beef in it. These ends usually have beef between the Asians and the Blacks. E6 ends, westernly at Green Street- which is a central place for Asian people - (where Barking Road meets Green Street up until Forest Gate), easternly at Barking Road (where the A406 meets the rest of the motorway/freeway), northernly at Plashet Grove (where High Street North meets Plashet Grove and East Road) and Southernly (where High Street South meets Lonsdale Ave and Beckton, although part of Beckton are still considered E6.

- All those boys are reppin E.6. we can't mess with them
- E.6. brehs are minor you ain't got nothing to worry about.
- E.6. is the same as E6.

E6 by x.F.x May 30, 2006

E6 

Christine Daae’s Highest note in The Phantom Of The Opera

SING FOR THE ANGEL OF MUSIC!
(Christine, hitting an E6.) AAAAAAAAAAAAAAAAAAAAAAAAA!!!!!!

E6 by LizardFeet March 19, 2019

E6 

typically stupid yutes use this word to say theyre from a postcode from london e6 or e1 they would uaually put this infront of their usernames to show theyre a badman but theyre not

theyre typically wastemen

neekywilliam_E6
E1_killermanshanker

E6 by verifyingshxt June 8, 2019

e621 

a website mostly made out of NSFW furry artwork, there are some SFW but everyone ignores them

It is also home to a lot of cursed artworks

Person 1: yo, check out this WoW porn I found!
Person 2: Hell Nah, I'd rather jack off to the shit on e621 than see that shit

e621 by ThunderTheFurry October 25, 2020

e621 

a place where can find a lot of furry porn and be able to sort by many different categories like if you were looking at rule 34

me: alright guys im going to jack off to furry porn on e621

my friend: wait what the fuck

e621 by zeno the protogen November 28, 2020