e621 

a website mostly made out of NSFW furry artwork, there are some SFW but everyone ignores them

It is also home to a lot of cursed artworks

Person 1: yo, check out this WoW porn I found!
Person 2: Hell Nah, I'd rather jack off to the shit on e621 than see that shit

e621 by ThunderTheFurry October 25, 2020

e621 

a place where can find a lot of furry porn and be able to sort by many different categories like if you were looking at rule 34

me: alright guys im going to jack off to furry porn on e621

my friend: wait what the fuck

e621 by zeno the protogen November 28, 2020

E621 

It's the E number for Monosodium Glutamate (aka MSG).

The furry imageboard with the same name most likely named itself E621 to address how 'tasty' their content is.

Funnily enough, there's a forum named E926 (the E number for bleach) that exists as an eye-bleach after one views the 'tasty' content of E621.

Person 1: E621 is love, E621 is life

Person 2: Ew, miss me with that furry shit

E621 by Obv troll is obvious March 23, 2021

E621 

E-number for Monosodium Glutamate, a common food additive that has a distinct umami taste.

Also refers to a particular website...

Alice: E621 tastes really good!
John: What's E621?
Alice: You'll soon find out...

E621 by レム July 23, 2020

e621 

e621 is an image board focused on furry artwork as well as other fetish art.. Do you know what furries are? You should.

Much of the content is pornographic in nature, and it contains many hardcore fetishes. Its cleaner counterpart is e926.

"e621 is a cursed website."

e621 by Deutsches Kaiserreich March 2, 2020

E621 

1. (n) Monosodium glutamate (MSG), a type of food additive.
2. (n) A website which is made mostly for furry pornography art.

Customer: Hey waiter, did you add E621 in my dish?
Waiter: What? No! Where do you see porn art in your steak?
Customer: Not that kind of e621, I talking about the additives- wait how do you know it’s furry porn?
Waiter: Ummmmmm fuck you.
Chef: WHERES MY FUCKING LAMB SAUCE

E621 by DBS dude March 29, 2022

e621 

Monosodium glutamate (msg) or furry porn

e621 is a porn website

e621 by Nfhsjfhh May 4, 2022