Top definition
a website mostly made out of NSFW furry artwork, there are some SFW but everyone ignores them

It is also home to a lot of cursed artworks
Person 1: yo, check out this WoW porn I found!
Person 2: Hell Nah, I'd rather jack off to the shit on e621 than see that shit
by ThunderTheFurry October 25, 2020
Get the merch
Get the e621 neck gaiter and mug.
Apr 18 Word of the Day
Joe: my mom died yesterday

John: bruuhh

Joe: Yo my mom just won million dollars

John: bRuHhh

Joe: my mom made dinner for us
John: bruh
by I eat forks with noodles October 30, 2019
Get the mug
Get a Bruh mug for your boyfriend Vivek.
2
e621 is an image board focused on furry artwork as well as other fetish art.. Do you know what furries are? You should.

Much of the content is pornographic in nature, and it contains many hardcore fetishes. Its cleaner counterpart is e926.
"e621 is a cursed website."
by Deutsches Kaiserreich March 02, 2020
Get the merch
Get the e621 neck gaiter and mug.
3
E-number for Monosodium Glutamate, a common food additive that has a distinct umami taste.

Also refers to a particular website...
Alice: E621 tastes really good!
John: What's E621?
Alice: You'll soon find out...
by レム July 23, 2020
Get the merch
Get the E621 neck gaiter and mug.
4
a place where can find a lot of furry porn and be able to sort by many different categories like if you were looking at rule 34
me: alright guys im going to jack off to furry porn on e621

my friend: wait what the fuck
by zeno the protogen November 28, 2020
Get the merch
Get the e621 neck gaiter and mug.
5
One of the Seven Circles of internet Hell, where furries and other stains on humanity flock. Some call it the off-brand rule34, while for others this is their most-visited site. Usually used as a gallery for both NSFW and SFW art. Porn posted here typically is composed of ponies, anthromorphic animals with human features, cartoons and various video game characters, ranging from Ankha from Animal Crossing to Ren & Stimpy. Some more well-known characters are : Various Pokemon, MLP characters and even Deathclaws from the Fallout series. Art is organized by tags that tell one or more things in the image. e621 is also home to porn that takes things to the extreme.
Person 1 : Dude, have you seen how sexy this gardevoir is? I found it on e621
Person 2: You know I'm into horses, right? And rule34 is the better site .
by PanisInTheAnus October 26, 2017
Get the mug
Get a e621 mug for your Uncle James.
6
e621 is a furry artwork site that is mainly known for it's furry NSFW, or yiff. Commonly used in memes as well.
Furry: Hey, do you use e621?
Non-furry: I went on there accidentally once, it wasn't good.
by Virtual-B December 16, 2020
Get the mug
Get a e621 mug for your coworker Paul.

Activity