Inspired by the popular MTV Veejay, "Dropping a Quddus" means to take a large, long awaited shit usually at one's home toilet during the afternoon while TRL is on.

Synonymous with "Dropping a Star Jones."
"Dude, do not go into that bathroom for a couple minutes. I just finished dropping a Quddus."
by N.Sharma October 11, 2007
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