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Doles comes from the word 'indole hallucinogen', which refers to the basic structure of the molecule that is similar to serotonin, which basic structure is call an indole nucleus. These are found in psychedelics such as LSD and Psilocybin.
Dude, I went to Burning Man last weekend, took some doles, and the music was sooooooo groovy.
Doles by Misohorny May 31, 2018
Doles refers to psychedelics that are indole hallucinogens, due to their basic structure being similar to serotonin, which basic structure is called an indole nucleus. Doles normally refers to LSD or Psilocybin.
Dude, I just came back from Burning Man, and I took so many doles, it was so groovy.
Doles by Misohorny May 31, 2018
A combination of nicotine and weed or dab pens
Friend 1: Yo can i borrow ur juul to take some doles
Friend 2: ya only if i can borrow ur pen for some doles after
Friend 1: word lets get shitty
Doles by SKATMAN14 October 6, 2019
A combination of nicotine and weed/ dab pens.
Friend 1: yo can i borrow ur juul to take doles
Friend 2: ya sure can i borrow ur pen after to take doles
Friend 1: word lets get shitty
Doles by SKATMAN14 October 6, 2019

Bob Doles 

Impotence; inability to get or sustain an erection. From former senator Bob Dole's admissions to erectile "difficulties" while commercial spokesman for Viagra.
I wanted to tap this hoochie yesterday but got the bob doles when I saw that hairy vag.

Or

I was so drunk I got the bob doles and couldn't perform.
Bob Doles by YupJimmy1 December 30, 2005
Mia is funny girl. Mia is a bad bitch literally all Mia Doles is very thick according to a bunch of guys Mia is someone you want to be friends with but not someone to talk shot about because if she finds out she will not be scared to kick your ass
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briefcake 

"Did you check out the briefcake in courtroom C?"
briefcake by Ben Frey April 6, 2006
Word of the Day on November 3, 2026
Brought to public attention by Bob Woodward and Carl Bernstein in the book on the fall of Richard Nixon, All The President’s Men, ratfucker was Nixon’s term for a political operative who sows chaos among opponents; an agent provocateur. It is thought to have originated among campus political rivalries at USC, and seems to have some usage in the US military.
Along with Nixon’s other ratfuckers, Roger Stone caused fights at otherwise peaceful Democratic Party protests to generate a false narrative that the Democrats were violent and dangerous.
Ratfucker by Ricky Ramjet November 2, 2017
Word of the Day on November 2, 2026
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