Pronounced dizástá tástrəfee

Cleverly put together words Disaster and Catastrophe.

1.) A situation which may be called a disaster or catastrophe or even worse, both.

Original Source - Said by "Ted Bear" in one of Cyanide and Happiness' YouTube videos.

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-Example-
Ted Bear - "Here's the scenario, you're on an international flight and the best has gone dodgy. Perhaps a albatross with poor eyesight has confused your plane engine for a mate and smacks right into it! Muckin' up your one snug commute to a spiraling disastatastrophe.
by SantaGuyDudePerson December 21, 2011
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