When individuals (or groups) originally from the capital cities of the world (or metropolitan) assume an air of superiority over everyone else. Cities where the problem is prevalent include; London, Edinburgh, Belfast, Dublin, Paris, Athens, Rome, Berlin, Vilnius, Vienna, Barcelona, Lisbon, Oslo, Stockholm, Helsinki, Washington, D.C., Mexico City, Ottawa, Cape Town, New Delhi, Beijing and Tokyo.

The phenomenon (disease) is mainly confined to Europe, North America and the developed english speaking world. However we cannot rule out its existence elsewhere.
Bar and club social scenario in Edinburgh

Man 1: "Hey bro, have you noticed how Sebastian from London and his bitches are staring at us?"
Man 2: "Yes indeed, it seemed to happen more once we told them we were from Leicester."

Man 1: "Yeah that condescending look, down the nose and all that. As if he's above."
Man 2: "Bro I know, but don't worry that mandem has capital city syndrome - its like just because theres a political office

in his city and its richer with more of a cultural hub. He somehow thinks it defines his superior nature."

Man 1: "Narcissistic Wankers"
Man 2: "Indeed, yeah apparently even Edinburgh folks and Dublin folks are also afflicted with the disease! Its like

everyone else in the counties doesn't matter!"
by The_Resurrected October 10, 2018
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