.io is the thing after a series of online games that is very popular
Agar.io lets play. Slither.io lets play that. Nope splix.io. and others
by Deltablue March 25, 2017
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doctor: you have cancer
patient: oh no
doctor: to be specific,you have cancer.io
patient: *fucking dies*
by gearworks June 17, 2018
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One of the four Galilean moons of Jupiter, so called because of being discovered by Galileo. The most volcanically active object in the Solar system.
Hey, look in my telescope: you can see Io, Europa, Ganymede, and Callisto.
by antinous February 2, 2004
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The mobile operating system for Apple mobile products. Android and iOS are direct rivals. Personally, I believe Android is better for more advanced users, and iOS is for users who want a more simpleminded experience.
iOS is developed and maintained by Apple. It was created by Steve Jobs.
by Bhamilton0347 November 15, 2014
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Kimmie nicknamed herself IO after falling for Ben's crap for time one hundred. I hate to agree but he sure doesn't seem to care much about her feelings.
by Shyantha December 20, 2006
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Acronym (Slang) for "I'm Out" when conversing using the Microsoft Communicator Software. v. The act of hastily departing an online collaboration session with little notice to others participating in the dialogue.

I am no longer part of this conversation as it is digressing rapidly; it will inevitably over-step that invisible moral line in the sand that uniquely distinguishes the employed from the homeless.
"Dude, I wanna dip it in the new workstudy sittin in the corner desk..."
<end of converstion>
by Big G Funk November 3, 2008
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Instant Orgasm, used by girls to describe something they find attractive and or hot.
"Wow! that sports car is cool." "Yeah! its a total IO."
by aussieslang101 November 12, 2009
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