1. Become influenced by drugs or Foreign substances...in a bad way
2. IT. To say you fixed something on a PC or Server when you really broke it, and really broke it goood.
2. IT. To say you fixed something on a PC or Server when you really broke it, and really broke it goood.
1. maaaan... I'm so tweaked out, I vomited all over myself while driving on the Motrway
2. IT. Tim Black the ginga...grrr
2. IT. Tim Black the ginga...grrr
by Bob is u're auntie October 16, 2008

In a conversation with someone you are trying to pick out a solution to a maths sequence and suddenly your brain recoginses the pattern........you tweaked to the idea being used.
by Mr Berry, Moon July 31, 2012

by Gordo352 April 22, 2006

A word most often used with the pretext "to pull a", this meaning of the word originated in Arroyo Grande, and refers to a resident who own a .50 cal handgun, and is the definintion of "badass"
by k man gg May 7, 2009

"Gave who some dam money? I aint gave no nobody no damn money girl! IS YOU TWEAKING!?" By R-kelly Real Talk
by HondaKiller2TGR June 18, 2008

by yolandaishurr February 18, 2011
