tweaking

1. High on DXM
2. High on speed

Dude, you are totally tweaking.

by Epigone July 2, 2003

Tweak

A word most often used with the pretext "to pull a", this meaning of the word originated in Arroyo Grande, and refers to a resident who own a .50 cal handgun, and is the definintion of "badass"

Victor: Yo! Come watch me smoke this fool!
Tyler: Hey man! Calm down, you're about to pull a Tweak!

by k man gg May 6, 2009

Tweaking

To do crack or act like doing crack/cocaine.

Most of the time used in a question

"Gave who some dam money? I aint gave no nobody no damn money girl! IS YOU TWEAKING!?" By R-kelly Real Talk

by HondaKiller2TGR June 19, 2008

Tweak

Thaaa coolest kid in south park

tweak is cool

by tweak July 19, 2003

tweak

a girl thats always wanting to get it in

that freshman be tweakin all ova the place. this is her fourth abortion

by yolandaishurr January 28, 2011

Tweak

A meth addict who is stuck doing pointless actions for long periods of time.

After hours of tweak activities, Theodore finally fell asleep.

by Juice Jonson February 26, 2018

Tweak

To stimulate a female's clitoris to the point of a micro-orgasm.

To the theme song tune of 'Kim Possible'. Call me beep me if you wanna tweak me.

by Kimfuckable May 3, 2019