Going to see a movie, and having to sit through so many commercials and trailers, you're either too tired-out or have lost all patience and don't feel like watching the goddamn movie anymore.
Phil: "How was the movie?"

Andrew: "I dunno... left before it began and got a refund because I got major trailer fatigue after sitting through 30 minutes of previews and the film still hadn't started yet."
by TeddyStix July 8, 2015
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The predictable mindset of helplessness and futility realized as a consequence of failing, long-term attempts at Pandemic management.
I just can't sustain all of these high-level protective restrictions...I'm going CRAZY!!!
You're not crazy; you just have Pandemic Fatigue. Sadly, the virus does not care and will take advantage of ANY opportunity to exploit human nature.
by YAWA July 4, 2020
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The feeling of being tired of the constant barrage of trump words on the top list
Holy crap another trump word i am have serious trump fatigue right now
by Elegendary December 5, 2016
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(n)
1. An unfortunate side affect of buttsex, butt fatigue affects 1 in 2 gay people
Malcolmb had such bad butt fatigue that he couldnt sit down for a week.
by Josh Krumbein February 9, 2006
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Combat stress reaction (CSR) is a term used within the military to describe acute behavioral disorganization seen by medical personnel as a direct result of the trauma of war. Also known as "combat fatigue" or "battle neurosis", it has some overlap with the diagnosis of acute stress reaction used in civilian psychiatry. It is historically linked to shell shock and can sometimes precurse post-traumatic stress disorder (PTSD).

Combat stress reaction is an acute reaction that includes a range of behaviors resulting from the stress of battle that decrease the combatant's fighting efficiency. The most common symptoms are fatigue, slower reaction times, indecision, disconnection from one's surroundings, and the inability to prioritize. Combat stress reaction is generally short-term and should not be confused with acute stress disorder, post-traumatic stress disorder, or other long-term disorders attributable to combat stress, although any of these may commence as a combat stress reaction. The US Army uses the term/acronym COSR (Combat Stress Reaction) in official medical reports. This term can be applied to any stress reaction in the military unit environment. Many reactions look like symptoms of mental illness (such as panic, extreme anxiety, depression, and hallucinations), but they are only transient reactions to the traumatic stress of combat and the cumulative stresses of military operations.
"Apparently, all of the eidos involved in the Pacific War ended up with combat fatigue."
by Outis McGuffin April 27, 2018
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1. The feeling achieved when eating the same type of food for a period of time.
Though one may still be hungry, they do not want anymore of the given food.
1. Guy 1 "Man these Burger King Flavored Onion Rings are delicious. I just can't seem to finish them."

Guy 2 "Do you want some of my chocolate?

Guy 1 "Yeah, that should help off-set my taste fatigue."
by Andy Orem March 23, 2009
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feelings of exhaustion, being stuck, and not being willing to continue to work on improving oneself that typically sets in after some time in a recovery program or rehab/treatment facility.
My sponsor wants me to work on that fourth AA step, but I just can't do it. I'm suffering from recovery fatigue.
by mumksh December 8, 2016
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