Goofball 

When you're acting like a silly nincompoop.

Jonny: *Barks at the water fountain*
Jay: You little goofball! Stop it."

Goofball by Mr.Slimy December 12, 2022

Goofball 

Someone who tends to drive around in their free time and spends less time studying the weather

Evelyn is a goofball.

Goofball by anonymous July 18, 2024

Goofball 2 

It means your a basic jake, but i guess ur kinda cool

How your such a Goofball 2 Sasha

Goofball 2 by anonymous May 23, 2021

goofball jenkins 

you are a goofball named jenkins

a: you are such a goofball jenkins
b: shut up you nig-

cops: POLICE OPEN UP

goofball jenkins by ayosussybaka69420 March 7, 2023

Atomic Goofball

The goof to end all goofs, this bboy comes from Maryland. He started bboying at a young age, but tragedy struck when he had to have chest surgery, seemingly ending his career early. But the goofy one kept his head up and became stronger than ever. Now a member of the legendary Lions of Zion and Battle Snakes, Goofball has proven himself over the years to be not only a competitor and legend of bboying, but a well needed jokester in an all to serious culture.

Bboy 1: Yo, who's that throwing down an atomic floating kneespin?
Bboy 2: Why none other than ATOMIC GOOFBALL!

Atomic Goofball by Bboy Maestro February 8, 2010

Glyceraldehyde Goofball 

So, I think I worked this out. It's mentioned in a scene in PLL (Pretty Little Liars) S3E16, and means that Toby is Spencer's sweet drug that makes her delusional, because Glyceraldehyde is a sweet aldose, and a Goofball is a slang term for a Barbiturate.
(See also Goofball)

"You're my Glyceraldehyde Goofball"
"Erm. What?"
"My sweet sweet drug!"
"Right..."

Glyceraldehyde Goofball by the__sp00ned March 6, 2015

hepped up on goofballs

To be intoxicated with illegal substances.

The driver involved with the hit & run incident appeared to be hepped up on goofballs

hepped up on goofballs by Dr. Zoidberg December 8, 2002