When you mix heroin and crystal meth together in a shot. West coast slang.
That goofball sent me to the moon for hours.
by dabqueen710 June 04, 2016
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Formerly and through the late 1980s anf 1990s, slang for barbiturates. Later expanded in common vernacular to include benzodiazepines (such as Xanax and Valium).

Commonly used today to describe the recreational combination and use of heroin and methamphetamine via IV injection.
When cooking up a hit of dope, "I got a couple points of shards, too; you wanna slam a goofball?"
by Fuckingspiders October 03, 2016
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Someone who is silly or stupid. Also looks silly or stupid.

Opposite of a chill bro.

People generally laugh at them than with them.
A: Do you know Declan?
B: Nah, I don't.
A: You know, the massive goofball?
B: Oh, yep! He's the king of goofballs.
by Double Denim Ranga August 02, 2010
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A term often used to describe a pretty girl when she does something adorable. Despite her sassy demeanor that often produces caustic one-liners that can put any cocky son of a bitch in his/her place, she has enough spark to attract a long list of Starbucks’ lovers.
Jermaine: Homie, I wish I had a goofball to brighten up maaaa lyfe!
D’Shawn: Son, you know Sharon’s single, nomsayin’ B?
Jermaine: Daaaaaaaaaaaayummmmm, she a real goofball, Imma get those digits.
by goofbaws February 07, 2015
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Someone who acts funny or silly to make others happy because they themselves cannot, so they try to hide it and help others before themselves.
L: wanna see how many socks I can fit in my mouth?!
K: You’re a goofball.

L: Hell Yeah I am!
by Sendaddy September 21, 2018
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Your ride and die buddy. Someone that's aloof and silly asl and has something you don't (if you're a girl). Goof + ball = Goofball
u/creativename62 : Soo, how'd you come up with Goofball

his future gf: I wanted it to be wholesome and funny. So, 'goof' for your personality and weird ways and 'ball' for something I don't have. :D

him: Bruh
by YeshQueen June 04, 2021
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