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and what 

Roughly equates to "so what". Can also mean absolutely nothing, depending on the context.

Context usually found in England, or at least London, is during the build-up to a fight in order to start something.
And what? You startin? And what?
and what by Someone else March 23, 2005

oh god mini wheat what are you doing at the nuremberg trials 

Suddenly, Mini-Wheat is put on trial. It's accidental, but the judge is unaware. He sits in fear, nervous of what the judge will do- because of what he's done to the other people. It's 1945, so "Mini-Wheat Discrimination" has not been put into place yet. He is sentenced to immediate execution. No more Mini-Wheat, kids.
Judge: Next is Mini-Wheat.
Everyone: oh god mini wheat what are you doing at the nuremberg trials

It is what it Is 

What incredibly vapid, stupid and unoriginal people say when they cannot construct a proper thought, retort or sentence.
If you were to ask a nitwit why he left work early, the response would go something like this. I don't know, I mean, I just felt ...I left early. It is what it is.

Or, when you catch a person in a lie, scheme or have proven them wrong in any way, It is what it is is sure to leak from their gaping mouth.

Or, to be dismissive. You promised me a dollar raise a month ago and it hasn't appeared in my check yet.

Well, it is what it is
It is what it Is by Jason JD August 19, 2007

S' what I do for a livin' nigga! 

What you do to get the mean green so you can put dubz on your whip. Its your job, not your career.
Todd: "I saw you cleaning poop off the shitter in the shopping mall bathrooms."
Tyrone: "Yah, S' what I do for a livin' nigga!"
Todd: "LOLOLOLOLOLOL............ by the way I like your new rims."

it is what it is 

1. Humble resignation to the circumstances of a situation that are beyond your control.

2. Euphemism for having little regard for outcome of a situation that will have a negative effect on those around you.
Example 1. It is a shame that Jimmie has left, but it is what it is.

Example 2. It's unfortunate you had to work late last night, but you know, it is what it is.
it is what it is by rsdsgnist March 3, 2010

OwO What's this?

me: *notices bulge* OwO What's this?
him: dude wtf