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durban poison

I just smoked some Durban Poison that my friend smuggled from South Africa. Now that is some quality weed.
by ikilled50cent April 18, 2005
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Irony poisoned

When someone perceives nearly everything through multiple layers of irony, and nothing through sincerity. This could extend to someone not being able to sincerely express their own beliefs without someone else thinking they’re being ironic or Insincere. And it could also extend to the inability of someone to take sincerity coming from others at face value, or being skeptical of it.
Person 1: I really enjoy X
Person 2: I bet you only like it because it’s secretly a coping mechanism for something else.
Person 1: it’s not, you’re brain is just irony poisoned
by L+Ratio? May 25, 2022
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POSO'D

When a person's argument or opinion has been ruled incorrect and invalid due to facts, logic, and Poso receipts.
"You've been poso'd, bro!"
by kp_06012007 March 20, 2021
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high speed lead poisoning

Slang for being shot.
Well, he does have 5 bullet holes in his body, so I'd guess the cause of death would've been high speed lead poisoning!
by Bangboy October 12, 2005
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Poso

The best promo code in the world, saving you tons of money so you can get the best sleep possible.
Use the promo code Poso at checkout on MyPillow.com to get the best sleep of your life!
by Rumpel1 May 12, 2021
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pessoptimist

A pessimist and an optimist. An individual who combines pessimism and optimism into a cohesive worldview that is neither purely negative nor wholly positive. They are distinct from a realist as they do not engage in a pragmatic approach to life. Rather, they are the quintessential happy-sad person.
A pessoptimist is someone who sees the the glass as both half empty and half full, enjoying the fullness as much as despising the emptiness.
by Zek J. Evets December 30, 2016
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poisonhole

A disparaging term used for an anal aperture that is intolerably stinky.
My dear, I do believe that your adorable little puppy may have poisonhole!
by Dr Bunnygirl June 19, 2021
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