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the big one 

It's the one people always talk about, the mythical/legendary big one. why isn't it already defined?
Refers to anything big, a big piece of food, a big sex organ, a big butt, or anything else that is big.
Hah! He bit the big one!
the big one by wichita March 17, 2008

The Big Oof 

Cancer, Usually transferred through memes
The Big Oof by Thanos March 4, 2019

sucking the big one 

Original know as sucking the big dick, sucking the big one describes anyone who is sucking terribly at what ever they do.
John: Wow I just failed that test.

Garnet: Wow you're sucking the big one today John.
sucking the big one by jcat47 December 11, 2007

The Big One 

the best big brother ever even though he is also the biggest a-hole in the world...it is out of love...Also another way to differentiate between a Sr. Dad and a Jr. Son
The Big One by Bubba69420 January 27, 2009

Doing the big one 

1. Another name for Sexual intercourse
2. Intense sexual intercourse
3. Kinda like "doing the nasty" but different name
4. Fucking every day all the time
Steve has sex every day, so he's doing the big one

John's in another room, and you hear humping. He's doing the "big one".
Doing the big one by cguy20 April 17, 2010

'The big one' 

Filling a balloon with semen and using it to bludgeon a family member or friend.
Mum, Harry is using 'the big one' on me!
'The big one' by Nut in it November 21, 2021