Sis 

A perfect response to your friend saying something stupid, bitchy, slutty or just something u can't think of a reply to

Person 1: Idk which guy to meet this weekend, there's a choice of 3
Person 2: sis

Sis by Theteakeeper January 12, 2019

sis 

an incredibly annoying yet popular term used mainly by teenage girls. “sis” or “sister” originated from the popular yet toxic youtuber james charles. the word usually replaces someone’s name in a phrase, and it not meant to be offensive for the most part. can be used rudely though, as seen in example 2. word for the wise, try to keep the number of times you use this word a day to 0.

ex 1: “omg! spill the tea sis!!”
ex 2: “don’t even go there sis, you look like a rat.”

sis by riley0 March 29, 2019

sis 

You want to call yourself or other person.

Sis(me) will not forget what sis(you) have done.

sis by Sis Deli August 6, 2018

sis 

A sis is a bump which women may get on their breast which is just a build up of fluid but often thought to be a cancerous bump.

My aunti went to the doctors yesturday to see about that bump on her lower breast but it wasnt cancer, it was a sis thank God.

sis by Justin [Future RAF Policeman] May 5, 2007

sis 

So It Seems

Given photographic evidence it appears that the parties in question where somewhat aloof, or SIS...
(an abbreviation for social media eg. Twitter)

sis by Asgard January 12, 2017

SIS 

It stands for Sunway International School.

SIS is a private school that based on Canadian Syllabus located in Subang Jaya.

SIS by MalaysiaBoleh October 24, 2017

sis 

used if mad at someone or you are spilling tea

“hey rebecca, i just beat you in gamepigeon.”
“SIS”

“sis i have tea ☕️”
“SIS SPILL”

sis by anonymous November 28, 2018