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An adjective, typically used to describe a rude or discourteous person, most commonly in conjunction with the operation of a motor vehicle.

Examples of such behavior might include, but should not be limited to: tailgating, lane drifting, weaving, random stopping, randomly leaving a turn signal on, not using a turn signal to indicate a turn, inability to merge, inability to yield, inability to observe posted signs for anything, or any combination of these.
Just ride on the Mass Pike. Multiple examples will immediately come to mind.
Masshole by Andrew February 9, 2004
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Maskhole 

Assholes who dont wear masks publicly during the Coronavirus/COVID 19 Pandemic. Especially common in NYC and usually of a certain perceived privaledge and political party(GOP).
That fucking MASKHOLE rolled up behind us like a Stealth Bomber as we were getting off the ferry on 34th street. Running and coughing, spreading that Rona all over the back of our necks. Not a mask or bandana in sight!
Maskhole by StayGoldJGold April 26, 2020
Word of the Day on April 27, 2020

Maskhole 

selfish idiots in my neighborhood who think that they don't need to wear a mask because the rest of us do
A maskhole jogged right past me in the park today
Maskhole by Bethinslope May 11, 2020
Word of the Day on July 11, 2020

Maskholes 

That segment of the population that ignores Science & decides wearing a mask is not for them. Meanwhile, potentially infececting those around them.
Did you see all the Maskholes at Home Depot today? Not one of them was wearing a mask!
Maskholes by 8 Mile July 22, 2020
Massachusetts + Asshole = Masshole
I'm a masshole and I'm proud of it!
Sox and Pats kick ass!
masshole by JasonGiambi December 10, 2004

Maskhole 

Someone who refuses to wear a safety mask for selfish reasons during a global pandemic.
My Dad thinks COVID-19 is a hoax & refuses to wear a mask… What a maskhole!
Maskhole by stxnthamix July 20, 2020
Guy or Girl from Massachusetts who expresses love by busting your balls. All others bow to them because they're jealous of their ruleitude. They talk fast, walk fast, drive fast, think fast and no one gets their sense of humor because it is dripping with sarcasm. WE are proud of it, because we know that the rest of the country is too plebeian to understand the complexity of awesome that is us.
YoI'maMassholeGetthefuckouttamywayyacunt!Igotmoreawesomeinmylittlefinger.Westartedthiscountry,bitch!
Masshole by KateTheGrate August 13, 2010