To tell someone to go away or to just leave you alone or never talk to them ever again.
PJ: Hey can i eat dinner at your house ?
AJ: yeah right, go fuck yourself.
ahhaha
COMEBACK: if your a male or female and an ugly opposite person of sex tells you to "go fuck yourself", you should reply :"I'd rather be fucking myself then fucking you". ahhaha
(1) method of dismissal
(2) A game that 90% of republicans and 85% of democrats need to go play
(1) You are talking too much, why don't you go play Hide-and-Go-Fuck-Yourself
(2) We would all be better off if politicians, idiot talking heads, and the idiots who worship them would go play Hide-and-Go-Fuck-Yourself while the rest of us try to work things outs
A command for someone to get lost (especially from the person that says it), usually as a result of extreme annoyance. Literally it means for them to masturbate themselves, so they aren't inclined to harrass and receive sexual pleasure from the person they are annoying. It's more stinging than "fuck off" because it implies that they could not or should not find anyone else to have sex with, so they need to use the self-manipulation.