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You can't fight city hall 

You cant fight corporate America! They are big and we are small! You can't fight city hall!
Thats Conglomo. They even own City Hall. And you know what they say! You can't fight city hall!

you can't polish a turd

unconvincingly attempt to make an irreconcilably bad situation look good.
They're trying to portray the poor financial reports as positive, but you can't polish a turd.

you can't unfuck the christmas turkey 

Another way of saying you cant undo something that's already been done. Can be said in a joke like way
You can't unloose the game you know, just like you can't unfuck the christmas turkey

You can't shoot me, I'm AIDS! 

A way of telling someone on a forum or other discussion that you disagree with them and their argument is so without merit you don't even need to put up a counter argument.
You can't shoot me, I'm AIDS!

you can't get there from here 

1. The place is remote and the route is hard to describe

2. the problem cannot be solved.
I'll say you can't get there from here. Let's just leave it at that.

You can't fire me because I quit syndrome 

The inability to accept the inevitable or obvious after an event has already happened.
Boss: You're fired!
Loser: You can't fire me, because I QUIT!
Boss: I don't know what you're quitting- I already fired you.
Loser: I QUIT, ya hear?! QUIT!!
Boss (to Secretary): Barbara, call security. We've got another case of "You can't fire me because I quit syndrome"