A particularly strong or annoying enemy in a singleplayer video game, typically a boss or other non-recurring entity.
Guy playing video games: "God, this boss has killed me like ten times now!!"
Guy's friend: "That's a Big Oof Nibba right there. Sorry, man"
Guy's friend: "That's a Big Oof Nibba right there. Sorry, man"
by captconan June 4, 2018

by The Lag Guy March 23, 2020

by Shrek's Large Toe January 10, 2019

When something is vastly and obviously failed, mistaken, or bad. You would use this word if usually if someone just majorly fails.
Me: Dude you just died to the the biggest bot in the whole world!
Friend: Stares at the screen in disbelief and ready to throw a temper.
Me: That’s a big oof right there!
Friend: Stares at the screen in disbelief and ready to throw a temper.
Me: That’s a big oof right there!
by BlackPepeSucky June 21, 2019

by I think moto moto likes You ;) March 19, 2019

by John Treehouse February 6, 2021

what tumblr girls say in response to anything you say; usually something negative that they don’t know how to respond to.
by dino.cogs October 16, 2019
