The same as the popular phrase, "oof", Boof is the the danker version of oof that is used mostly by meme and parody accounts on Instagram and Twitter.
by Legeogame May 30, 2018

we gone smoke a phat BOOF tonight y’all.
les smoke a boof.
u gone roll up da boof?
when we burnin the boof
les smoke a boof.
u gone roll up da boof?
when we burnin the boof
by lilbitchh April 10, 2019

The sound made by a large dog, like a St. Bernard. Similar to a bark, but less aggressive and more lazy sounding.
What sound does a cat make? “Meow.” What sound does a horse make? “Neigh.” What sound does a duck make? “Quack.” What sound does a doge make? “Boof.”
by YeetXD November 20, 2017

by It's the Real Deal October 21, 2018

"Pass the boof," I said and then smoked the boof.
"Dude... that shit hits hard." I then said as I shit myself.
"Dude... that shit hits hard." I then said as I shit myself.
by ddiggety October 11, 2019
