A combination of "whats up dog?" and "whats up though" making it both a freindly greeting and a question at the same time. Origins in Rochester and Detroit Michigan.
Usually this involves taking a less expensive item (usually a car or a musical instrument) and adding lots of after market (custom) parts to make the item look or work better. Sometimes it can involve more expensive items. Many times this saying can replace retrofitting. Always involves making the item more expensive and better looking.
"I just picked up a brand new Honda Civic and I am going to Sup It Up with a twin turbo and a cold air intake!"
"I bought a Fender Stratocaster and I am going to Sup It Up with some $900 humbuckers!"
Sup Muff? is a phrase that can be used in a variety of ways. It can be used to express pleasure, pain, confusion, elation, sadness, and a wide range of emotions. The phrase is typical among High School students in the south east Pennsylvania and Central New Jersey area.