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No, Charles!

An expression used to express helplessness, or a potential "Oh SHIT" moment, Essentially when you realize you are helpless to prevent an adverse occurrence from happening.
As i ran up the steep and muddy hill, I began to slip, and as I grabbed small trees to gain my footing in vain, I yelled "No Charles!"
"No, Charles!" popularized in the "im the juggernaut bitch" video when the Shiar chick shoots the helmet off his head that usually protects him from Professor CHarles Xavier's telepathic abilities.
by Pat in the effin hat April 21, 2006
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charleston

A gorgeous, old city in southern South Carolina. Not to be mixed up with North Charleston.
I went to Charleston and fell in love.
by SCgirl September 22, 2005
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Charles Darwin

An English Naturalist who was the author of “Origin of Species” as well as several other books. Charles Darwin revolutionized biology with the scientific theory of evolution. Evolution is Descent with modification. Change in the genetic composition of a population during successive generations, as a result of natural selection acting on the genetic variation among individuals, and resulting in the development of new species. This is a scientific fact and the theory of evolution has never been disproved much as some would like to see that happen.

For some reason this inspires great hostility among people who have obviously never read or done research on evolution. (As evidenced by the questions about why are there still apes. Answer: Evolution isn’t a ladder, it more like a tree that has many branches. Humans didn’t evolve from modern day apes such as chimpanzees… humans and chimps have a common ancestor. The descendents of that common ancestor split off into different species over millions of years. )
Charles Darwin had ten children, three of whom died early. Many of his surviving children and their grandchildren would later achieve notability themselves.
by OneBadAsp November 3, 2006
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James charles

The gayest person who has ever lived
OH MY GOD I NEED THE NEW JAMES CHARLES MAKEUP KIT!” -white girls
by realegmoney January 6, 2019
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Charlieissocoollike

A (very good-looking) british twenty something year old who writes songs and vlogs. Very popular on youtube with over one million subscribers.
Nerimon: Have you seen Charlieissocoollike's latest video?
Obssed fan: *squealing* yes, yes ,yes, yes!!
by leprachaun ninja November 24, 2011
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Charlea

Charlea is a fine ass sassy girl. She is smart, pretty, fine, cute, she’s just everything. Charlea has a boyfriend so I wouldn’t fuck with her. Charlea does not fuck with the drama shit.
If you can get Charlea, you are special.
by Hella.thick February 23, 2019
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Cavalier King Charles Spaniel

Breed of dog that origingated in England a long friggin time ago. They were the royal dog until the pug was introduced. Looks a lot like a Cocker Spaniel, but nothing like it. Cocker Spaniels are stupid. Cavaliers are the best pets ever.
What kind of a dog is that? 'It's a Cavalier King CHarles Spaniel, you idiot!'
by Abby April 4, 2005
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