Permafized

When a person does too much acid or shrumes and their systems are messed up even when they are not on the influence of Acid or Shrumes.

"Dude, that guy is going to be Permafized if he parties like this every night."

by Permafized June 2, 2009

permafried

smoking so much weed that you are known to have S.R.D. (stupid retarded disorder). also known as "William Fisher."

that kid is permafried!

by willie wonka520 July 7, 2008

Permafried

When youve done too many drugs in a short amount of time youre permanently fucked up/ retarded

Also known as a Matthew Ramo.

"Dont be a matt ramo, wait a couple weeks before you trip again or you'll be permafried."

by Fanxis August 16, 2017

Permatize

To make a temporary solution permanent.

The temporary cable was permatized by running it under the data center floor.

by Shades Russ March 31, 2021

permafried

When someone has done so much dope in their life that they end up in a perpetual state of slowness and stupidity

That guy takes forever to explain shit, he's so permafried

by numbnuts33 March 25, 2025

Permafried

**Permafried**

*adjective*

A state in which one's brain is permanently impaired or "fried" due to excessive or reckless substance use, resulting in chronic mental fog, diminished cognitive function, or erratic behavior that persists indefinitely.

**Example**: After hitting those sketchy black market weed pens nonstop for months, Braden’s totally permafried—guy can barely string a sentence together now.

by Jxckkk May 12, 2025

Permafried

A person who's enjoyed alot of meth over a long period of time, and has literally cooked there brain.

Don't worry bout her bro, she's permafried.

Does she always ramble nonsense to her self? Yea cuz she's permafried

by Alex " big dick" Lewis January 5, 2026