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Poopie is part of the "Poopie and Explodie" duo from a Ren and Stimpy Cartoon.
Explodie: "I have to throw up now, Poopie!"
poopie by Ross January 15, 2004
(1) To take a shit.
(2) Pet name used for small dogs such as poodles.
(1) "I just made poopie on the congressman's car!"
(2) "Who's my wittle poopie doopy?"
poopie by KaiserMonkey August 19, 2003
the poop that comes out when you poop in a weird way
(pooping 90 degrees, standing up, no lid, most popular, in diapers.)
the baby went poopie
poopie by pieser me niger April 17, 2011
Hey Paul I'm coming to your house now, but first..... Let me take a POOPIE.

JOHNNY WAS HERE. Then he took a POOPIE and left. He posted it on Facebook.
Poopie by iplaynaked May 25, 2014
When someone you know and respect lays a dump in your toilet and doesn't flush it.
Hey, Joty just went to the bathroom, laid a dump, and didn't flush it! What a poopie!
poopie by marrymary July 17, 2011
gang word for “let’s kill those hoes
poopie by crackfairychristina June 21, 2019