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A problem of the male genitalia such as an STI, a direct hit by an oject (accidental or meant) or the worst kind, catching of said weapon in the flies of your trousers
"what's up John mate? You're walking a little gingerly" "oh Les, took one to the hang down off one of the kids this morning and its throbbing" "quick, get John some ice he's got a right knoblem
knoblem by coyneezy July 26, 2009
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Knobsickle 

My boyfriend has a knobsickle
Knobsickle by furrylampshade2543 November 9, 2009
Related Words

knowledge integration 

The practice of combining knowledge across disciplinary boundaries and collaborating with diverse specialists in order to tackle complex problems.

There's an unusual and demanding arts and science degree in knowledge integration offered at the University of Waterloo. However, having a piano doesn't make you a musician.

"When a book and a head collide and a hollow sound is heard, must it always have come from the book?" — Georg Christoph Lichtenberg
When I graduate from med school, I will be trained to practice medicine. Whether I'm any good at it depends on me and how I study, work and learn. When I graduate from Knowledge Integration I will be trained to collaborate with peers from many disciplines.
Knoof, or Kn00f may refer to:

A combination spoon and knife that is particularly suited to preparing peanut-butter and jelly sandwiches.

-or-

A derogatory slang term that can refer to sexual acts, domination, or destruction.
I used a knoof to eat my dinner.

I used a knoof to eat your mother.

I was totally kn00fed by the other players in COD last night.

I walked in on them knoofing.
Knoof by Snicker Bungley May 11, 2010

knocker rocker 

A nice little knocker rocker and then I came on her face. It was epic.
knocker rocker by Kran zee pants August 17, 2010

Knob lob 

The act of lobbing a grenade across the playing field, random with no reason, in games such as Call of Duty.
I SWEAR IF I GET KILLED BY ONE MORE KNOB LOB I WILL JUMP OUT OF MY WINDOW.
Knob lob by a912 December 16, 2010

Knows his way around Istanbul 

The ability to bring a woman to orgasm using three fingers and a smoldering gaze.
No need to worry about Jim's chances of scoring tonight, that's a dude who knows his way around Istanbul.