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this hits different 

After Daniel Howell posted his iconic coming out video, old fans suddenly logged into their old phan accounts to repost old fan edits with the title being ''hits different". This lead to fans going back to old dan and phil videos and commenting the same. It then spread to videos that weren't even related to phan at all.
dan from 2010- "fyi, i like vagina."
phil from 2010- "same"
Phandom: "This hits different"

two different people 

A phrase describing two individuals who have very little to nothing in common, in terms of personalities, interests, opinions and/or beliefs. A softer way to say that two people are generally uncomfortable in each other's presence and because of the resulting tensions are unlikely ever to get along or even be able to stand one another.
Dave doesn't talk to his father anymore. They're just two different people who never saw eye-to-eye on anything.

Coming different 

Ooh my sis is coming different😍
Coming different by Starlight221 November 25, 2018

built different 

built different means you aint like everyone else or just built different which is often used as a meme.
Person 1: Why did you stay up all night
Person 2: Idk i am just built different
and
Person 1: i didn't sleep last night, guess im just built different
built different by ✓reddit October 3, 2020

A different change of clothes 

Something anime characters don't have.
Anime characters have the same change of clothes. They need a different change of clothes.

Same Issue, Different Tissue 

The same old shit occurring from the same old shitty people!
That slut bag WHORE banged my skinny, faggot boss. Same issue, Different Tissue!